Schematic of the Finkelstein reaction. Reagents: alkyl halide, acetone, NaCl, NaBr, NaI. Product: substituted alkyl halide, metal halide precipitate (ppt). Comments: Equilibrium shifts to the right as the newly formed salt precipitates.

The Finkelstein reaction is an organic reaction where an alkyl halide is converted into another alkyl halide by reacting with a metal halide salt. 2,4-Dichloro-6-ethylpyrimidine Formula Price of 1633667-60-3 This is an equilibrium process and it is driven forward by taking advantage of the poor solubility in acetone of the newly formed metal halide salt (Le Chatelier’s principle). The mechanism for this reaction is a simple, single-step bimolecular nucleophilic substitution reaction (SN2) which like all SN2 reactions occur with inversion of stereochemistry. [1]

Mechanism

Mechanism of the Finkelstein reaction.

References:

1.
Finkelstein, H. Ber. Dtsch. Chem. Ges. 1910, 43, 1528–1532.