The Grignard reaction is an organic reaction used to create a variety of products through the reaction of an organomagnesium compound, also known as a “Grignard reagent” with an electrophile, followed by acid work-up. (S)-1,2,3,4-Tetrahydronaphthalen-2-amine Order (1-Phenylvinyl)boronic acid custom synthesis The Grignard reagent is formed through the reaction of an alkyl or aryl halide with magnesium metal via a radical mechanism. The mechanism of the subsequent reaction of the Grignard reagent with the electrophile is debatable. The most popular proposals are a “concerted mechanism” or another “radical mechanism”, both can explain the final addition product. ^[1][2]