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AGE (2013) 35:1545557 DOI 10.PMID:23381601 1007/s113570129457zAntiaging effects of vitamin C on human pluripotent stem cellderived cardiomyocytesYoon Young Kim SeungYup Ku Yul Huh HungChing Liu Seok Hyun Kim Young Min Choi Shin Yong MoonReceived: 19 January 2012 / Accepted: 6 July 2012 / Published on line: 28 July 2012 # American Aging AssociationAbstract Human pluripotent stem cells (hPSCs) have arisen as a source of cells for biomedical research because of their developmental prospective. Stem cells possess the promise of supplying clinicians with novel treatment options for disease at the same time as permitting researchers to create humanspecific cellular metabolism models. Aging is really a natural approach of living organisms, but aging in human heart cells is tough to study due to the ethical considerations regarding human experimentation at the same time as a current lack of alternative experimental models. hPSCderived cardiomyocytes (CMs) bear a resemblance to human cardiac cells and hence hPSCderived CMs are regarded as to be a viable option model to study human heart cell aging. In this study, we applied hPSCderived CMs asY.
