Product Name :
Nuclear Receptor Corepressor Mouse Monoclonal Antibody [A6H12]
Predicted band size :
270 kDa
Observed band size :
270 kDa
Synonyms:
hN CoR antibody hNCoR antibody KIAA1047 antibody N CoR antibody N Cor/SMRT corepressor Rip13 antibody N CoR1 antibody N-CoR antibody N-CoR1 antibody NCOR 1 antibody NCoR antibody 展开
Function :
This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p.Formula of 5-Chloro-3-methyl-1H-pyrazole This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17.(2-Cyclopropylpyridin-4-yl)boronic acid web Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 17 and 20.
Antibody Type:
Mouse Monoclonal Antibody
Immunogen :
Recombinant protein within human Nuclear Receptor Corepressor aa 251-450.
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IHC-P
Coupling :
unconjugated
Clone number:
A6H12
RRID:
AB_3071672
Form :
Liquid
Concentration :
2ug/ul
Storage instructions:
Store at +4℃ after thawing.PMID:33675606 Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
Storage buffer solution:
PBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG1
Purification method :
Protein G affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 270 kDa
Positive control :
Jurkat cell lysates, HeLa cell lysates, rat kidney tissue, human colon tissue, human breast carcinoma tissue, human kidney tissue, mouse small intestine tissue..